The extensive beds of aquatic vegetation, high water quality, shelter from strong winds and wave action, and undeveloped shoreline areas, create highly favorable conditions for spawning and nursery use by many warm water fish species. Included among these are bowfin, northern pike, largemouth bass, brown bullhead, rock bass, pumpkinseed, bluegill, black crappie, and yellow perch. Several uncommon species, such as yellow bullhead and chain pickerel are also found in the area. Lake of the Isles is a major concentration area in the river for many of these species, and is especially renowned for its largemouth bass population. Many trophy size bass have been taken here (including the St. Lawrence River record), attracting fishermen from
throughout the Thousand Islands region. Many anglers are also attracted to Lake of the Isles by its excellent year-round fisheries for pike and various pan fish species. Access to the area for recreational fishing is available from De Wolf Point State Park and from private facilities on the bay and at nearby river locations.